[A case of juvenile colon cancer with peritoneal dissemination treated effectively by use of resection and chemotherapy].

Abstract

A 37 -year-old man experienced abdominal pain and vomiting. Computed tomography showed massive ascites and obstruction of the colon by a tumor at the left colic flexure. The tumor was classified as advanced Borrmann type 3 on the basis of a colonoscopy. Palliative resection of the colon and colostomy on the oral side were performed. Operative findings showed massive peritoneal dissemination of the tumor. We administered palliative chemotherapy consisting of capecitabine/oxaliplatin (XELOX) and bevacizumab. After 4 courses of chemotherapy, the primary and disseminated tumors and ascites had disappeared, and tumor marker expression levels were within normal range. Palliative resection and subsequent chemotherapy was effective for this young patient with very advanced colon cancer that had disseminated and caused obstruction.

• Authors: Kimihiro Yonemitsu, Shunji Kawamoto, Hiroshi Maeno, Shouichi Okubo, Seiji Hosaka, Satoshi Umemoto, Takahisa Yoshida, Chitoshi Ohara
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 41 Issue 12 Pg. 1695-7 (Nov 2014) ISSN: 0385-0684 [Print] Japan
• PMID: 25731299 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Oxaloacetates
• Deoxycytidine
• Capecitabine
• Fluorouracil

Topics

• Adult
• Antineoplastic Combined Chemotherapy Protocols (administration & dosage, therapeutic use)
• Capecitabine
• Colonic Neoplasms (drug therapy, pathology, surgery)
• Colostomy
• Combined Modality Therapy
• Deoxycytidine (administration & dosage, analogs & derivatives)
• Fluorouracil (administration & dosage, analogs & derivatives)
• Humans
• Male
• Oxaloacetates
• Peritoneal Neoplasms (drug therapy, secondary)