Fine-needle aspiration of superficial myxoid neurofibroma in the region of the breast.

Abstract

Myxoid neurofibromas are benign spindle cell tumors of perineural cell origin with a broad pathologic differential diagnosis, which includes myxoma, myxoid liposarcoma, myxoid dermatofibrosarcoma protuberans, and low-grade fibromyxoid sarcoma. We present an unusual case of superficial myxoid neurofibroma in the region of the breast that underwent pre-operative fine-needle aspiration (FNA). The differential diagnosis for a myxoid subcutaneous lesion should include myxoid neurofibroma when myxoid material is encountered in an otherwise hypocellular FNA.

• Authors: MacLean P Nasrallah, Ilya M Nasrallah, Gordon H Yu
• Journal: Diagnostic cytopathology (Diagn Cytopathol) Vol. 43 Issue 5 Pg. 427-31 (May 2015) ISSN: 1097-0339 [Electronic] United States
• PMID: 25722038 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2015 Wiley Periodicals, Inc.

Chemical References

• Biomarkers, Tumor
• S100 Calcium Binding Protein beta Subunit
• S100B protein, human

Topics

• Adult
• Biomarkers, Tumor (genetics)
• Biopsy, Fine-Needle
• Breast (pathology)
• Dermatofibrosarcoma (diagnosis, genetics, pathology)
• Diagnosis, Differential
• Female
• Fibrosarcoma (diagnosis, genetics, pathology)
• Humans
• Liposarcoma, Myxoid (diagnosis, genetics, pathology)
• Myxoma (diagnosis, genetics, pathology)
• Neurofibroma (diagnosis, genetics, pathology)
• S100 Calcium Binding Protein beta Subunit (genetics)
• Skin (pathology)