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Retroperitoneal liposarcoma: current insights in diagnosis and treatment.

Abstract
Retroperitoneal liposarcoma (RLS) is a rare, biologically heterogeneous tumor that present considerable challenges due to its size and deep location. As a consequence, the majority of patients with high-grade RLS will develop locally recurrent disease following surgery, and this constitutes the cause of death in most patients. Here, we review current insights and controversies regarding histology, molecular biology, extent of surgery, (neo)adjuvant treatment, and systemic treatment including novel targeted agents in RLS.
AuthorsLucas E Matthyssens, David Creytens, Wim P Ceelen
JournalFrontiers in surgery (Front Surg) Vol. 2 Pg. 4 ( 2015) ISSN: 2296-875X [Print] Switzerland
PMID25713799 (Publication Type: Journal Article, Review)

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