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[Is this mitral valve prolapse? A case of mitral regurgitation with early systolic murmur due to early systolic prolapse of the posterior leaflet].

Abstract
This paper reports the findings of phonocardiograms, echocardiogram and Doppler echocardiograms in a case of a 50-year-old man with early mitral valve prolapse with an early systolic murmur. A characteristic early systolic crescendo murmur was recorded at the apex. By amyl nitrite inhalation, the early systolic murmur was attenuated and a late systolic murmur was evoked. On the contrary, methoxamine injection increased the intensity of the early systolic murmur. Early systolic prolapse and early systolic buckling were recorded by two-dimensional and M-mode echocardiography. The phase of mitral regurgitation detected by M-mode color Dopper echocardiography coincided well in timing with the early systolic murmur and the early systolic buckling recorded on the M-mode echocardiogram. A discussion was made on the mechanism of the early systolic mitral regurgitation due to early mitral valve prolapse.
AuthorsT Ishimitsu, Y Hiranuma, Y Sugishita, I Ito
JournalJournal of cardiology. Supplement (J Cardiol Suppl) Vol. 21 Pg. 97-105, discussion 106-8 ( 1989) Japan
PMID2570865 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Amyl Nitrite
  • Methoxamine
Topics
  • Amyl Nitrite
  • Echocardiography
  • Echocardiography, Doppler
  • Heart Auscultation
  • Heart Murmurs
  • Humans
  • Male
  • Methoxamine
  • Middle Aged
  • Mitral Valve Insufficiency (etiology, physiopathology)
  • Mitral Valve Prolapse (complications, diagnosis, physiopathology)
  • Myocardial Contraction
  • Phonocardiography
  • Systole

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