Abstract | BACKGROUND: Symptomatic sacral perineural cysts are a common cause of chronic pain. Surgery is one choice for symptom relief but has a high risk of cyst recurrence and complications. As a simple and safe method to manage symptomatic sacral perineural cysts, C-arm fluoroscopy-guided fibrin gel injection may represent a new minimally invasive alternative. To evaluate the efficacy of this new method, we conducted a retrospective study of 42 patients. METHODS AND FINDINGS: From June 2009 to August 2012, a total of 42 patients with symptomatic sacral perineural cysts underwent C-arm fluoroscopy-guided percutaneous fibrin gel injection therapy. Patient outcomes in terms of improvements in pain and neurologic function were evaluated during a follow-up period of 13-39 months. The preoperative and postoperative pain severity were assessed according to a 10-cm visual analog pain scale, and imaging changes were evaluated by magnetic resonance imaging. We also assessed postoperative complications. Most patients experienced benefit from the procedure: twenty-five patients (59.5%) reported excellent recovery, eleven (26.2%) reported good recovery, three (7.1%) reported fair recovery, and three (7.1%) reported poor recovery. The overall effectiveness rate (excellent and good recoveries) was 85.7%. No serious postoperative complications were observed. CONCLUSION: Percutaneous fibrin gel injection under C-arm fluoroscopy guidance could be a simple, safe and effective treatment option for symptomatic sacral perineural cysts.
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Authors | Wei Jiang, QuanHe Qiu, Jie Hao, XiaoJun Zhang, Wei Shui, ZhenMing Hu |
Journal | PloS one
(PLoS One)
Vol. 10
Issue 2
Pg. e0118254
( 2015)
ISSN: 1932-6203 [Electronic] United States |
PMID | 25706639
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Female
- Fibrin
(administration & dosage)
- Fluoroscopy
(methods)
- Humans
- Injections
(methods)
- Male
- Middle Aged
- Neoplasm Recurrence, Local
(prevention & control)
- Retrospective Studies
- Tarlov Cysts
(therapy)
- Young Adult
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