Abstract |
A 59-year-old Japanese man was admitted to our hospital for treatment of a submucosal tumor of the esophagus detected by upper gastrointestinal endoscopy and computed tomography (CT). Endoscopic examination revealed a submucosal tumor in the esophagus 35 cm from the incisor teeth. Biopsy of the lesions identified granular cell tumor. CT indicated a projecting and slightly enhanced homogenous mass measuring 2.0 × 1.5 cm in the esophagus below the tracheal bifurcation. Serum tumor marker studies revealed elevated carbohydrate antigen (CA) 19-9. Therefore, the tumor was considered to have malignant potential, and surgical resection was performed. The final pathologic diagnosis was a benign granular cell tumor, positive for S-100 protein. The patient was doing well with normal CA 19-9 levels and no recurrence more than 5 years after surgery. To the best of our knowledge, this is the first report of a granular cell tumor with elevated serum CA 19-9.
|
Authors | Toru Yanoma, Minoru Fukuchi, Shinji Sakurai, Hisanori Shoji, Hiroshi Naitoh, Hiroyuki Kuwano |
Journal | International surgery
(Int Surg)
Vol. 100
Issue 2
Pg. 365-9
(Feb 2015)
ISSN: 2520-2456 [Electronic] Italy |
PMID | 25692443
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Antigens, Tumor-Associated, Carbohydrate
- carbohydrate antigen 199, human
|
Topics |
- Antigens, Tumor-Associated, Carbohydrate
(blood)
- Esophageal Neoplasms
(blood, diagnostic imaging)
- Granular Cell Tumor
(blood, diagnostic imaging)
- Humans
- Male
- Middle Aged
- Tomography, X-Ray Computed
|