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Granular cell tumor of the esophagus with elevated preoperative serum carbohydrate antigen 19-9: a case report.

Abstract
A 59-year-old Japanese man was admitted to our hospital for treatment of a submucosal tumor of the esophagus detected by upper gastrointestinal endoscopy and computed tomography (CT). Endoscopic examination revealed a submucosal tumor in the esophagus 35 cm from the incisor teeth. Biopsy of the lesions identified granular cell tumor. CT indicated a projecting and slightly enhanced homogenous mass measuring 2.0 × 1.5 cm in the esophagus below the tracheal bifurcation. Serum tumor marker studies revealed elevated carbohydrate antigen (CA) 19-9. Therefore, the tumor was considered to have malignant potential, and surgical resection was performed. The final pathologic diagnosis was a benign granular cell tumor, positive for S-100 protein. The patient was doing well with normal CA 19-9 levels and no recurrence more than 5 years after surgery. To the best of our knowledge, this is the first report of a granular cell tumor with elevated serum CA 19-9.
AuthorsToru Yanoma, Minoru Fukuchi, Shinji Sakurai, Hisanori Shoji, Hiroshi Naitoh, Hiroyuki Kuwano
JournalInternational surgery (Int Surg) Vol. 100 Issue 2 Pg. 365-9 (Feb 2015) ISSN: 2520-2456 [Electronic] Italy
PMID25692443 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antigens, Tumor-Associated, Carbohydrate
  • carbohydrate antigen 199, human
Topics
  • Antigens, Tumor-Associated, Carbohydrate (blood)
  • Esophageal Neoplasms (blood, diagnostic imaging)
  • Granular Cell Tumor (blood, diagnostic imaging)
  • Humans
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed

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