Abstract |
We report the case of a 64 year-old woman who demonstrated resolution of recalcitrant, generalized granuloma annulare (GA) following treatment with adalimumab. After showing little response to other treatment techniques, such as steroids and a triple antibiotic regimen, the patient was started on adalimumab. Within 3 months, she showed almost complete resolution of lesions. Within 6 months, she was completely lesion-free, and remained clear following 12 months of adalimumab therapy. This case provides further evidence that tumour necrosis factor-α inhibitors may be a treatment option for patients with recalcitrant, generalized GA.
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Authors | T Mahmood, B Mansouri, A Menter |
Journal | Clinical and experimental dermatology
(Clin Exp Dermatol)
Vol. 40
Issue 5
Pg. 537-9
(Jul 2015)
ISSN: 1365-2230 [Electronic] England |
PMID | 25688452
(Publication Type: Case Reports, Journal Article)
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Copyright | © 2015 British Association of Dermatologists. |
Chemical References |
- Anti-Inflammatory Agents
- Antibodies, Monoclonal
- Tumor Necrosis Factor-alpha
- Adalimumab
|
Topics |
- Adalimumab
(therapeutic use)
- Anti-Inflammatory Agents
(therapeutic use)
- Antibodies, Monoclonal
(therapeutic use)
- Female
- Granuloma Annulare
(drug therapy)
- Humans
- Middle Aged
- Treatment Outcome
- Tumor Necrosis Factor-alpha
(antagonists & inhibitors)
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