[Hemorrhagic cystitis due to adenovirus in a renal transplant recipient: the first reported case in black Africa in a setting of a very beginning of a kidney transplantation program and review of the literature].
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| Abstract |
Viral infections are an important complication of transplantation. Polyomavirus are the commonest viruses that infect the renal allograft. Herpes virus nephropathy has also been described. In the past 15 years, adenovirus nephritis has emerged as a potentially life-threatening disease in renal transplant patients in developed countries. Most of the papers devoted to adenovirus nephritis are reported cases. The fate of such patients in resources-limited countries is not known. Herein, we describe the clinical, biological and prognostic findings of a black African transplanted patient with adenoviral hemorrhagic cystitis. This case is the very first of its kind reported in black Africa in a setting of a start of a renal transplantation pilot project. The patient is a 54-year-old man admitted at the nephrology service for gross haematuria and fever occurred 1 month after kidney transplantation. The diagnosis of adenoviral hemorrhagic cystitis has been suspected because the patient has displayed recurrent conjunctivitis and gastroenteritis well before transplantation, which was then confirmed by the real-time polymerase chain reaction performed on the blood. Conservatory measures associated with immunosuppression reduction have permitted the discontinuation of haematuria. This case has been discussed in regard of the epidemiology, the diagnosis, the treatment, the evolution and the prognosis of the adenoviral infection in the renal transplant patient. A review of the literature has been performed subsequently.
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| Authors | Clément Ackoundou-N'Guessan, Noël Coulibaly, Cyr Monley Guei, Denis Aye, Francis Yapi N'guessan, Justin Kouame N'Dah, Delphine Amélie Lagou, Mélanie Weu Tia, Pessa Albert Coulibaly, Sita Nzoue, Serges Konan, Daze Apollinaire Gnionsahe |
| Journal | Nephrologie & therapeutique (Nephrol Ther) Vol. 11 Issue 2 Pg. 104-10 (Apr 2015) ISSN: 1872-9177 [Electronic] France |
| Vernacular Title | Cystite hémorragique à adénovirus chez le transplanté rénal: à propos d'un premier cas en Afrique noire survenu dans un tout débutant programme de greffe rénale et revue de la littérature. |
| PMID | 25684056 (Publication Type: Case Reports, Journal Article, Review) |
| Copyright | Copyright © 2015 Association Société de néphrologie. Published by Elsevier SAS. All rights reserved. |
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