Abstract | INTRODUCTION: CASE PRESENTATION: A 19-year-old male patient had progressive myoclonus, GTCSs that often progressed to status epilepticus (SE), progressive cerebellar and extrapyramidal symptomatology, and dementia, and his disease was pharmacoresistant. We confirmed the diagnosis of LBD by genetic testing. After VNS implantation, in the one-year follow-up period, there was a complete reduction of GTCS and SE, significant regression of myoclonus, and moderate regression of cerebellar symptomatology. CONCLUSION: To our knowledge, this is the first reported case of the utility of VNS in LBD. Vagus nerve stimulation therapy may be considered a treatment option for different clinical entities of PME. Further studies with a larger number of patients are needed.
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Authors | Sanja Hajnsek, Zeljka Petelin Gadze, Fran Borovecki, Sibila Nankovic, Goran Mrak, Kristina Gotovac, Vlatko Sulentic, Ivana Kovacevic, Andreja Bujan Kovac |
Journal | Epilepsy & behavior case reports
(Epilepsy Behav Case Rep)
Vol. 1
Pg. 150-2
( 2013)
ISSN: 2213-3232 [Print] United States |
PMID | 25667850
(Publication Type: Journal Article)
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