Abstract | BACKGROUND:
De Quervain disease is a stenosing condition of the sheath of the abductor pollicis longus and extensor pollicis brevis tendons at the radial styloid process. Previous studies consistently reported that the pathological change of this condition is thought to be primarily an extensor retinaculum thickened by fibrosis and angiogenesis instead of inflammation. Contradictorily, the conservative treatment for de Quervain disease is anti-inflammatory medication. The inflammatory response may be involved in this disease; however, there is no present study directly evidencing whether the inflammatory responses exist in de Quervain disease or not. The histopathology of de Quervain disease is yet to be elucidated clearly. PURPOSE: To grade all specimens in the different stages and characterize specific inflammatory cell and factors to examine whether inflammatory response is involved in de Quervain disease. METHODS: RESULTS: CONCLUSIONS:
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Authors | Yao-Lung Kuo, Che-Chia Hsu, Li-Chieh Kuo, Po-Ting Wu, Chung-Jung Shao, Kuo-Chen Wu, Tung-Tai Wu, I-Ming Jou |
Journal | Annals of plastic surgery
(Ann Plast Surg)
Vol. 74 Suppl 2
Pg. S146-51
(May 2015)
ISSN: 1536-3708 [Electronic] United States |
PMID | 25650747
(Publication Type: Journal Article)
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Topics |
- Adult
- Aged
- De Quervain Disease
(complications, metabolism, pathology)
- Female
- Humans
- Inflammation
(etiology)
- Male
- Middle Aged
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