Plastic bronchitis associated with influenza virus infection in children: a report on 14 cases.

Abstract

BACKGROUND:

Plastic bronchitis (PB) is a rare disease characterized by formation of bronchial casts. It is usually associated with congenital heart disease, sickle cell disease, lymphoma, and lung diseases such as asthma and pneumonia.

OBJECTIVES:

To report 14 cases of PB with influenza A or influenza B infection.

METHODS:

We analyzed the clinical manifestations, bronchoscopic and histologic findings, clinical courses, and outcomes.

RESULTS:

These cases indicate that PB is a life-threatening complication of severe influenza. Plastic bronchitis should be considered in the diagnosis of children with acute respiratory distress such as lung atelectasis accompanied by influenza.

CONCLUSIONS:

Diagnosis should be made by bronchial endoscopy and histopathology, and bronchial casts removed as early as possible.

• Authors: Jianhui Zhang, Xiaolei Kang
• Journal: International journal of pediatric otorhinolaryngology (Int J Pediatr Otorhinolaryngol) Vol. 79 Issue 4 Pg. 481-6 (Apr 2015) ISSN: 1872-8464 [Electronic] Ireland
• PMID: 25639552 (Publication Type: Journal Article)
• Copyright: Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Chemical References

• Antiviral Agents
• Glucocorticoids
• Oseltamivir

Topics

• Antiviral Agents (therapeutic use)
• Bronchitis (diagnosis, drug therapy, virology)
• Bronchoscopy (methods)
• Child
• Child, Preschool
• Drug Therapy, Combination
• Female
• Glucocorticoids (therapeutic use)
• Humans
• Infant
• Influenza A virus (isolation & purification)
• Influenza B virus (isolation & purification)
• Influenza, Human (diagnosis, drug therapy, virology)
• Male
• Mediastinal Emphysema (diagnosis)
• Oseltamivir (therapeutic use)
• Pneumothorax (diagnosis)
• Pulmonary Atelectasis (diagnostic imaging)
• Radiography
• Subcutaneous Emphysema (diagnosis)