Positive reactions to nickel on a patch test do not predict clinical outcome of nickel alloy-based atrial septal defect occluder implantation.

Abstract

BACKGROUND:

Patch testing is thought to be necessary prior to metal device implantation to rule out metal allergy-related complications; however, there are controversies over the effects of nickel allergy on the outcome of nickel alloy-based device implantation.

OBJECTIVE:

This study aimed to evaluate the adverse events in a Korean population of nickel allergy patients who underwent atrial septal defect (ASD) closure with a nickel-titanium alloy-based device.

METHODS:

We retrospectively reviewed the medical records of patients who underwent ASD closure with a nitinol device.

RESULTS:

Among 38 patients who had ASD closure, 4 of 5 nickel-allergic patients and 10 of the 33 non-nickel-allergic patients had post-closure complications. All patients fared well, without device failure culminating in device removal.

CONCLUSION:

In this study, positive reactions to nickel in a patch test were not associated with adverse early or late outcomes following ASD closure with a nickel alloy-based device.

• Authors: Hee Joo Kim, Jung U Shin, Jungsoo Lee, Hemin Lee, Shan Jin, Seo Hyeong Kim, Ji Yeon Noh, Kwang Hoon Lee
• Journal: Dermatology (Basel, Switzerland) (Dermatology) Vol. 230 Issue 2 Pg. 184-8 ( 2015) ISSN: 1421-9832 [Electronic] Switzerland
• PMID: 25634825 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2015 S. Karger AG, Basel.

Chemical References

• titanium nickelide
• Nickel
• Titanium

Topics

• Adult
• Female
• Heart Septal Defects, Atrial (therapy)
• Humans
• Hypersensitivity (diagnosis)
• Male
• Middle Aged
• Migraine Disorders (etiology)
• Nickel (adverse effects)
• Patch Tests
• Predictive Value of Tests
• Retrospective Studies
• Septal Occluder Device (adverse effects)
• Titanium (adverse effects)
• Young Adult