Abstract | BACKGROUND/PURPOSE: METHODS: A retrospective cohort study of 111 consecutive infants with gastroschisis. RESULTS: 64 episodes suggesting non- IgE-mediated CMPA occurred in 50 infants (45 %) at a median age of 44 days (9-186) and during the primary admission in 38 %. At the time of the episode the infant feed was breast milk (BM, n = 24), term formula (TF, n = 20) or extensively hydrolysed formula (EHF, n = 6). The feed was changed to EHF (34), amino acid formula (AAF) (14) or BM with maternal CMP-free diet (2). Partial or complete resolution of symptoms occurred in all. There was histological evidence of an allergic reaction to CMP in all four infants in whom tissue was available. Recurrent episodes occurred in 13/50 infants (26 %), 10 of whom were receiving EHF. There were no recurrent episodes in infants being fed with AAF. CONCLUSION: Features suggesting non- IgE-mediated CMPA appear common in infants with gastroschisis.
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Authors | David Burge, Melanie Drewett, Nigel Hall |
Journal | Pediatric surgery international
(Pediatr Surg Int)
Vol. 31
Issue 3
Pg. 271-6
(Mar 2015)
ISSN: 1437-9813 [Electronic] Germany |
PMID | 25627700
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Breast Feeding
- Cohort Studies
- Comorbidity
- Female
- Gastroschisis
(epidemiology, immunology)
- Humans
- Incidence
- Infant
- Infant Formula
- Infant, Newborn
- Male
- Milk Hypersensitivity
(epidemiology, immunology)
- Milk Proteins
(immunology)
- Retrospective Studies
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