Abstract | INTRODUCTION: METHODS: HCC1806 ( doxorubicin-sensitive) and MX-1 ( doxorubicin-resistant), cell lines were xenografted into nude mice and treated with MIA-602, doxorubicin, or their combination. Tumors were evaluated for changes in volume and the expression of the drug resistance genes MDR1 and NANOG. In-vitro cell culture assays were used to analyze the effect of MIA-602 on efflux pump function. RESULTS: CONCLUSIONS:
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Authors | Roberto Perez, Andrew V Schally, Petra Popovics, Renzhi Cai, Wei Sha, Ricardo Rincon, Ferenc G Rick |
Journal | Oncoscience
(Oncoscience)
Vol. 1
Issue 10
Pg. 665-73
( 2014)
ISSN: 2331-4737 [Print] United States |
PMID | 25593995
(Publication Type: Journal Article)
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