Abstract | BACKGROUND: MATERIAL & METHOD: In a double-blind clinical trial, 90 otherwise healthy parturients candidate of elective caesarean section were randomly allocated to receive lactated ringer's solution (1000 ml), sodium chloride 0.9% (1000 ml) or HES (7.5 mL/Kg) as preloading before spinal anesthesia. Hemodynamic parameters including blood pressure and heart rate, umbilical cord blood pH and the neonatal Apgar score were compared among the three groups. RESULTS: There was no difference in the basic hemodynamic measurements among the three groups. The incidence of hypotension and required dose of ephedrine was lower in HES group (p=0.008). There was no significant difference in umbilical cord blood PH or Apgar scores among intervention groups. CONCLUSION: Preloading with HES is more effective than crystalloids in prevention hypotension after spinal anesthesia without significant difference in Apgar score and umblical cord blood pH.
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Authors | Mahzad Alimian, Masood Mohseni, Reza Safaeian, Seyed Hamid Reza Faiz, Mohammad Azad Majedi |
Journal | Medical archives (Sarajevo, Bosnia and Herzegovina)
(Med Arch)
Vol. 68
Issue 4
Pg. 279-81
(Aug 2014)
ISSN: 0350-199X [Print] Bosnia and Herzegovina |
PMID | 25568553
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Hydroxyethyl Starch Derivatives
- Isotonic Solutions
|
Topics |
- Adult
- Anesthesia, Spinal
- Blood Pressure
(drug effects)
- Cesarean Section
- Double-Blind Method
- Female
- Heart Rate
(drug effects)
- Humans
- Hydroxyethyl Starch Derivatives
(administration & dosage, therapeutic use)
- Hypotension
(prevention & control)
- Isotonic Solutions
(administration & dosage, therapeutic use)
- Pregnancy
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