Prepubertal unilateral gynecomastia: report of 2 cases.

Abstract

Prepubertal unilateral gynecomastia is an extremely rare condition. At present, its etiology and management strategy are not well known. Two unrelated prepubertal boys of ages 8 and 9 who presented with complaints of unilateral enlargement of breast tissue are reported. Physical examination, biochemical, hormonal and oncologic work-up findings were normal. Both patients were treated with peripheral liposuction successfully. Histopathological and immunohistochemical examinations showed benign fibroglandular gynecomastia and intensive (3+) estrogen receptor expression in 100% of periductal epithelial cells. Although an extremely rare and generally benign condition, patients with prepubertal unilateral gynecomastia should have a full endocrine and oncologic work-up.

• Authors: Hüseyin Demirbilek, Gökhan Bacak, Rıza Taner Baran, Yahya Avcı, Ahmet Baran, Ayşenur Keleş, Mehmet Nuri Özbek, Yasemin Alanay, Khalid Hussain
• Journal: Journal of clinical research in pediatric endocrinology (J Clin Res Pediatr Endocrinol) Vol. 6 Issue 4 Pg. 250-3 (Dec 2014) ISSN: 1308-5735 [Electronic] Turkey
• PMID: 25541897 (Publication Type: Case Reports, Journal Article)

Topics

• Child
• Gynecomastia (diagnosis, surgery)
• Humans
• Male
• Puberty