Abstract |
Currently, there are no standardized, objective, and clinically applicable methods to predict the outcome of pulsed dye laser (PDL) therapy on capillary vascular malformation (CVM) patients. The introduction of a method that can predict the outcome prior to treatment will be valuable for both the patients and the doctors. In this study, the authors treated CVM with 595-nm wavelength PDL in Chinese patients (n = 686) and analyzed the efficacy of treatment and complications retrospectively in a 5-year period. Nearly 18 % of patients (n = 122) had 76 % or more clearing of lesions; over 52 % of patients (n = 360) had more than 50 % of clearing. The lesions in head and neck region had the best effective rate (58.3 %), followed by trunk (42.9 %) and extremities (35.6 %). The efficacy of PDL therapy is related to age, type, and location of lesions. Fifty-seven patients (8.3 %) had complications, including 2.0 % blistering (n = 14), 4.5 % hyperpigmentation (n = 31), 1.3 % hypopigmentation (n = 9), and 0.4 % hypertrophic scarring (n = 3). Based on these preliminary data, the authors established a standardized, objective, and clinically applicable equation that may be applied to predict the efficacy of 595 nm PDL therapy on a newly diagnosed Chinese CVM patients based on the age, type, and location of lesions.
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Authors | Xiangxia Liu, Yanfang Fan, Jiexin Huang, Ruixi Zeng, Guangling Cao, Mukai Chen, Wenna Chen, Jinming Tang |
Journal | Lasers in medical science
(Lasers Med Sci)
Vol. 30
Issue 3
Pg. 1041-6
(Apr 2015)
ISSN: 1435-604X [Electronic] England |
PMID | 25487186
(Publication Type: Journal Article)
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Topics |
- Adolescent
- Adult
- Aged
- Child
- Child, Preschool
- Female
- Humans
- Infant
- Lasers, Dye
- Male
- Middle Aged
- Pilot Projects
- ROC Curve
- Retrospective Studies
- Treatment Outcome
- Vascular Malformations
(pathology, surgery)
- Young Adult
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