Abstract | OBJECTIVE: RESULTS:
PAPP-A staining in tumor tissue was detected in 45 of 46 specimens. There were significantly greater extent and intensity of PAPP-A expression in luminal B specimens with high proliferation index than luminal A specimens (P = 0.01). However, there were no differences between specimens positive or negative for HER2 (P = 0.14) or positive and negative for estrogen receptor (P = 0.31). CONCLUSION:
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Authors | Aaron S Mansfield, Daniel W Visscher, Steven N Hart, Chen Wang, Matthew P Goetz, Claus Oxvig, Cheryl A Conover |
Journal | Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
(Growth Horm IGF Res)
Vol. 24
Issue 6
Pg. 264-7
(Dec 2014)
ISSN: 1532-2238 [Electronic] Scotland |
PMID | 25468445
(Publication Type: Journal Article, Research Support, N.I.H., Extramural)
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Chemical References |
- Biomarkers, Tumor
- ESR1 protein, human
- Estrogen Receptor alpha
- Receptors, Estrogen
- Receptors, Progesterone
- Pregnancy-Associated Plasma Protein-A
- PAPPA protein, human
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Topics |
- Aged
- Biomarkers, Tumor
(metabolism)
- Breast Neoplasms
(metabolism, pathology)
- Carcinoma, Ductal, Breast
(metabolism, pathology)
- Carcinoma, Lobular
(metabolism, pathology)
- Estrogen Receptor alpha
(metabolism)
- Female
- Humans
- Immunoenzyme Techniques
- Middle Aged
- Neoplasm Grading
- Neoplasm Staging
- Pregnancy
- Pregnancy-Associated Plasma Protein-A
(metabolism)
- Prognosis
- Receptors, Estrogen
(metabolism)
- Receptors, Progesterone
(metabolism)
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