Abstract | PURPOSE: To compare the six-month outcome of three different ultrasound-guided treatments for de Quervain's disease (DQD). METHODS: We prospectively treated 75 consecutive patients (51 females, 24 males, mean age ± standard deviation = 45.3 ± 9.8 years) with DQD. Patients' features (hand dominance, intraretinaculum septum, accessory tendons) were recorded. Visual analogue scale (VAS), reduced disability (quickDASH) score, and retinaculum thickness were evaluated at baseline and after one (excluding retinaculum thickness), three, and six months. Patients were randomized into three groups of 25 patients each treated under ultrasound guidance: Group A (1 ml methylprednisolone acetate; mean baseline thickness = 1.6 mm; mean baseline VAS = 6; mean baseline quickDASH = 55); Group B (1 ml methylprednisolone acetate +15-day delayed 2 ml saline 0.9 %; 1.4; 6; 56); Group C (1 ml methylprednisolone acetate +15-day delayed 2 ml low molecular weight hyaluronic acid; 1.7; 6; 55). RESULTS: After one month results were: Group A mean VAS = 2; mean quickDASH = 23; Group B 2; 22; Group C 2; 21. After three months results were: Group A retinaculum thickness = 0.7 mm; 3; 27); Group B 0.8 mm; 1; 25; Group C 0.5 mm; 1; 23. After six months results were: Group A 1.5 mm; 3; 51; Group B 1 mm; 2; 51; Group C 0.7 mm; 1; 26 (P < 0.001 for all vs. baseline). Patients' age, sex, hand dominance, presence of subcompartment dividing septum, and supernumerary tendons had no influence on outcome (P ≥ 0.177). CONCLUSION: KEY POINTS:
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Authors | Davide Orlandi, Angelo Corazza, Emanuele Fabbro, Giulio Ferrero, Giuseppe Sabino, Giovanni Serafini, Enzo Silvestri, Luca Maria Sconfienza |
Journal | European radiology
(Eur Radiol)
Vol. 25
Issue 5
Pg. 1512-9
(May 2015)
ISSN: 1432-1084 [Electronic] Germany |
PMID | 25465711
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anti-Inflammatory Agents
- Viscosupplements
- Methylprednisolone Acetate
- Sodium Chloride
- Hyaluronic Acid
- Methylprednisolone
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Topics |
- Adult
- Anti-Inflammatory Agents
(administration & dosage, therapeutic use)
- De Quervain Disease
(diagnostic imaging, drug therapy)
- Female
- Follow-Up Studies
- Humans
- Hyaluronic Acid
(administration & dosage)
- Injections, Intralesional
- Injections, Subcutaneous
- Male
- Methylprednisolone
(administration & dosage, analogs & derivatives)
- Methylprednisolone Acetate
- Middle Aged
- Prospective Studies
- Recurrence
- Sodium Chloride
(administration & dosage, therapeutic use)
- Treatment Outcome
- Ultrasonography, Interventional
(methods)
- Viscosupplements
(administration & dosage, therapeutic use)
- Wrist Joint
(diagnostic imaging)
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