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Quinolone and indole alkaloids from the fruits of Euodia rutaecarpa and their cytotoxicity against two human cancer cell lines.

Abstract
Four quinolone alkaloids (1-4) and three indole alkaloids (20-22), together with 30 known alkaloids (5-19, 23-37), were isolated from the fruits of Euodia rutaecarpa. Their structures were established by spectroscopic analyses. The in vitro cytotoxic activities of these alkaloids against leukaemia HL-60 and prostate cancer PC-3 cell lines were evaluated.
AuthorsNan Zhao, Zhan-Lin Li, Da-Hong Li, Ya-Ting Sun, Dong-Ting Shan, Jiao Bai, Yue-Hu Pei, Yong-Kui Jing, Hui-Ming Hua
JournalPhytochemistry (Phytochemistry) Vol. 109 Pg. 133-9 (Jan 2015) ISSN: 1873-3700 [Electronic] England
PMID25457491 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
CopyrightCopyright © 2014 Elsevier Ltd. All rights reserved.
Chemical References
  • Antineoplastic Agents, Phytogenic
  • Indole Alkaloids
  • Plant Extracts
  • Quinolones
Topics
  • Antineoplastic Agents, Phytogenic (chemistry, isolation & purification)
  • Evodia (chemistry)
  • Fruit (chemistry)
  • HL-60 Cells
  • Humans
  • Indole Alkaloids (chemistry, isolation & purification)
  • Male
  • Molecular Structure
  • Plant Extracts (chemistry)
  • Prostatic Neoplasms (pathology)
  • Quinolones (chemistry, isolation & purification)

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