Abstract |
Malignant pleural effusions cause significant morbidity, but there is no gold standard minimally invasive treatment. A new therapeutic approach combines talc pleurodesis and indwelling pleural catheters (IPCs) to enable outpatient management. This case series summarizes the safety and efficacy data of all patients (24) with a symptomatic malignant pleural effusion who underwent talc pleurodeses via IPCs between December 2010 and July 2013. Successful pleurodesis was achieved in 22 procedures (92%). There was one empyema, one hydropneumothorax, one recurrent effusion, and two minor complications: one drain site wound infection and one complaint of chest pain. Twenty-two procedures (92%) were performed in the outpatient setting. This report confirms the safety and efficacy of administering talc slurry through IPCs in an outpatient setting. Studies in a larger cohort are necessary to define the role of this novel approach in the treatment algorithm of patients with this condition.
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Authors | Liju Ahmed, Hugh Ip, Deepak Rao, Nishil Patel, Farinaz Noorzad |
Journal | Chest
(Chest)
Vol. 146
Issue 6
Pg. e190-e194
(Dec 2014)
ISSN: 1931-3543 [Electronic] United States |
PMID | 25451360
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Ambulatory Care
(methods)
- Catheters, Indwelling
- Cohort Studies
- Critical Pathways
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Patient Safety
- Pleural Effusion, Malignant
(diagnosis, mortality, therapy)
- Pleurodesis
(methods)
- Radiography, Thoracic
(methods)
- Retrospective Studies
- Risk Assessment
- Severity of Illness Index
- Survival Rate
- Talc
(therapeutic use)
- Tomography, X-Ray Computed
(methods)
- Treatment Outcome
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