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Hirschsprung disease and anorectal malformation.

Abstract
Hirschsprung disease and Anorectal Malformations are congenital disorders presenting in neonates with distal intestinal obstruction. Hirschsprung disease is associated with a functional distal bowel obstruction resulting from the abnormal development of the enteric nervous system and ensuing aganglionosis of the distal gut. Anorectal Malformations comprise a spectrum of anatomical anomalies causing a mechanical bowel obstruction. Both conditions are frequently associated with congenital abnormalities/syndromes, which require careful assessment and evaluation. Surgical intervention is usually required for both conditions with careful preparation and meticulous technique. Long-term follow-up allows early identification and treatment of potentially debilitating symptoms, which include faecal incontinence.
AuthorsCharlotte Wetherill, Jonathan Sutcliffe
JournalEarly human development (Early Hum Dev) Vol. 90 Issue 12 Pg. 927-32 (Dec 2014) ISSN: 1872-6232 [Electronic] Ireland
PMID25448783 (Publication Type: Journal Article, Review)
CopyrightCopyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Topics
  • Anorectal Malformations
  • Anus, Imperforate (complications, diagnostic imaging, surgery)
  • Guidelines as Topic
  • Hirschsprung Disease (complications, diagnostic imaging, surgery)
  • Humans
  • Infant, Newborn
  • Intestinal Obstruction (complications, diagnostic imaging, surgery)
  • Radiography

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