Hearing loss in a pediatric patient following cisplatin chemotherapy and subsequent exposure to excessive noise.

Abstract

Cisplatin is a commonly-used chemotherapeutic agent that is highly-effective against a variety of pediatric cancers. Unfortunately, it may lead to ototoxicity, with serious consequences on the quality of life of survivors. Patients remain at risk of progression of ototoxicity even after completion of treatment. We report the case of a medulloblastoma survivor with previously documented normal hearing, who developed significant hearing loss and tinnitus following exposure to excessive noise at a nightclub three years after completion of treatment. We highlight the importance of long-term audiological follow up and education about the increased risk of hearing loss in this population.

• Authors: Emilia Peleva, Emilie Aloy, Anne-Sophie Carret, Sam J Daniel
• Journal: International journal of pediatric otorhinolaryngology (Int J Pediatr Otorhinolaryngol) Vol. 78 Issue 12 Pg. 2301-4 (Dec 2014) ISSN: 1872-8464 [Electronic] Ireland
• PMID: 25439704 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Chemical References

• Antineoplastic Agents
• Cisplatin

Topics

• Adolescent
• Antineoplastic Agents (adverse effects)
• Brain Neoplasms (drug therapy)
• Cisplatin (adverse effects)
• Hearing Loss, Noise-Induced (diagnosis)
• Humans
• Male
• Medulloblastoma (drug therapy)
• Tinnitus (etiology)