Granular cell tumor of the stomach coincident with two early gastric carcinomas.

Abstract

In a 64-yr-old Japanese man, granular cell tumor of the stomach plus two early gastric carcinomas were detected. The granular cell tumor was a 1.5 x 1.5-cm submucosal nodule located in the posterior wall of the fundus. The mucosa adjacent to the granular cell tumor showed two well-differentiated adenocarcinomas restricted to the mucosa, but there was no continuity among these three conditions. This seems to be the first report of this type of association. Immunohistochemical study revealed S-100 protein in the component cells of the granular cell tumor, thereby supporting the proposal that this granular cell is derived from Schwann cells.

• Authors: K Yamaguchi, S Maeda, K Kitamura
• Journal: The American journal of gastroenterology (Am J Gastroenterol) Vol. 84 Issue 6 Pg. 656-9 (Jun 1989) ISSN: 0002-9270 [Print] United States
• PMID: 2543214 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antibodies, Neoplasm

Topics

• Adenocarcinoma (pathology)
• Antibodies, Neoplasm (analysis)
• Humans
• Male
• Middle Aged
• Neoplasms, Multiple Primary (pathology)
• Neoplasms, Muscle Tissue (immunology, pathology)
• Stomach Neoplasms (immunology, pathology)