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Current status of Paragonimus and paragonimiasis in Ecuador.

Abstract
A review of national and international publications on paragonimiasis in Ecuador, epidemiological records from the Ministry of Public Health and unpublished research data was conducted to summarise the current status of the parasite/disease. The purpose of the review is to educate physicians, policy-makers and health providers on the status of the disease and to stimulate scientific investigators to conduct further research. Paragonimiasis was first diagnosed in Ecuador 94 years ago and it is endemic to both tropical and subtropical regions in 19 of 24 provinces in the Pacific Coast and Amazon regions. Paragonimus mexicanus is the only known species in the country, with the mollusc Aroapyrgus colombiensis and the crabs Moreirocarcinus emarginatus, Hypolobocera chilensis and Hypolobocera aequatorialis being the primary and secondary intermediate hosts, respectively. Recent studies found P. mexicanus metacercariae in Trichodactylus faxoni crabs of the northern Amazon. Chronic pulmonary paragonimiasis is commonly misdiagnosed and treated as tuberculosis and although studies have demonstrated the efficacy of praziquantel and triclabendazole for the treatment of human infections, neither drug is available in Ecuador. Official data recorded from 1978-2007 indicate an annual incidence of 85.5 cases throughout the 19 provinces, with an estimated 17.2% of the population at risk of infection. There are no current data on the incidence/prevalence of infection, nor is there a national control programme.
AuthorsManuel Calvopiña, Daniel Romero, Byron Castañeda, Yoshihisa Hashiguchi, Hiromu Sugiyama
JournalMemorias do Instituto Oswaldo Cruz (Mem Inst Oswaldo Cruz) Vol. 109 Issue 7 Pg. 849-55 (Nov 2014) ISSN: 1678-8060 [Electronic] Brazil
PMID25410987 (Publication Type: Journal Article, Review)
Chemical References
  • Anthelmintics
Topics
  • Animals
  • Anthelmintics (therapeutic use)
  • Astacoidea (parasitology)
  • Brachyura (parasitology)
  • Chronic Disease
  • Ecuador (epidemiology)
  • Humans
  • Lung Diseases, Parasitic (diagnosis, drug therapy, epidemiology)
  • Metacercariae (isolation & purification)
  • Neglected Diseases (epidemiology)
  • Paragonimiasis (diagnosis, drug therapy, epidemiology)
  • Paragonimus (classification)

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