Abstract | BACKGROUND: CASE PRESENTATION: A 57-year-old Caucasian man with new onset diplopia was diagnosed with vertebral artery aneurysm extending into the basilar circulation. He underwent successful elective vertebral artery angioplasty and coiling of the aneurysm. In the immediate post-operative period there was a decline in his neurological status and brain imaging revealed new midbrain and thalamic hemorrhage with surrounding significant brain edema. Treatment with conventional anti- edema therapy was initiated with no significant clinical response after which conivaptan; a mixed vasopressin antagonist was started. Clinical and radiological evaluation following drug administration showed rapid clinical improvement without identification of significant adverse effects. CONCLUSIONS:
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Authors | Vishnumurthy Shushrutha Hedna, Sharathchandra Bidari, David Gubernick, Saeed Ansari, Irawan Satriotomo, Asif A Khan, Adnan I Qureshi |
Journal | BMC neurology
(BMC Neurol)
Vol. 14
Pg. 213
(Nov 18 2014)
ISSN: 1471-2377 [Electronic] England |
PMID | 25403760
(Publication Type: Case Reports, Journal Article, Review)
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Chemical References |
- Antidiuretic Hormone Receptor Antagonists
- Benzazepines
- conivaptan
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Topics |
- Antidiuretic Hormone Receptor Antagonists
(administration & dosage, pharmacology)
- Benzazepines
(administration & dosage, pharmacology)
- Brain Edema
(drug therapy, etiology)
- Humans
- Male
- Middle Aged
- Stroke
(complications)
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