Cytomegalovirus acute retinal necrosis in an immunocompetent patient after sub-tenon triamcinolone injection.

Abstract

PURPOSE:

To report a case of cytomegalovirus acute retinal necrosis after a sub-Tenon injection of triamcinolone acetonide in an immunocompetent patient.

METHODS:

A 77-year-old man received a sub-Tenon injection of triamcinolone acetonide for treatment of iritis unresponsive to topical steroids. He subsequently developed unilateral acute retinal necrosis.

RESULTS:

Vitreous biopsy with polymerase chain reaction analysis was positive for cytomegalovirus. Implantation of a sustained-release ganciclovir device resulted in disease stabilization.

CONCLUSION:

Cytomegalovirus can be a causative agent of both anterior uveitis and acute retinal necrosis. A potential complication of a sub-Tenon steroid injection may be viral reactivation causing acute retinal necrosis secondary to localized immunosuppression.

• Authors: Amy S Babiuch, Zac B Ravage, Pauline T Merrill
• Journal: Retinal cases & brief reports (Retin Cases Brief Rep) Vol. 4 Issue 4 Pg. 364-5 ( 2010) ISSN: 1935-1089 [Print] United States
• PMID: 25390918 (Publication Type: Journal Article)