Abstract | PURPOSE: METHODS: Retrospective interventional case report. Chart review. RESULTS: A 73-year-old white woman, who received monthly intravitreal bevacizumab injections for exudative age-related macular degeneration in the right eye, developed decreased vision 4 days after her last injection. She had trace anterior chamber cells and 1+ vitritis, consistent with a bevacizumab-associated uveitis. The patient improved on topical steroids and cycloplegics. Subsequently, her exudative age-related macular degeneration was treated with monthly ranibizumab injections. Optical coherence tomography demonstrated persistent subretinal fluid despite treatment. Seven days after her 11th ranibizumab injection, she developed sudden decreased vision, 2+ anterior chamber cell, and 4+ vitritis. Presumptive treatment for an exogenous bacterial endophthalmitis was given after a vitreous biopsy was performed, which demonstrated severe sterile infiltrates that were culture negative. All injections were stopped. Three months later, the subretinal fluid had disappeared, the vitritis has nearly resolved, but some intraretinal fluid persisted. CONCLUSION:
|
Authors | Matthew A Cunningham, Paul Tlucek, James C Folk, H Culver Boldt, Stephen R Russell |
Journal | Retinal cases & brief reports
(Retin Cases Brief Rep)
Vol. 7
Issue 4
Pg. 355-8
( 2013)
ISSN: 1937-1578 [Electronic] United States |
PMID | 25383816
(Publication Type: Journal Article)
|