Proposed objective visual system biomarkers for mild traumatic brain injury.

Abstract

The challenge and search for objectively based biomarkers to assess for the presence of concussion/mild traumatic brain injury is a high priority for the military establishment. We present a documented overview of specific test areas and related targeted, high-yield, objectively based parameters that may be potential "vision biomarkers" for the detection of concussion/mild traumatic brain injury based on results from our laboratory and others, with emphasis on oculomotor aspects. These findings have military relevance with respect to the initial diagnosis in the battlefield and in the far-forward medical facilities, pre-/postdeployment issues, pre-/postvisual rehabilitation evaluation, fitness-for-duty assessment, and establishment of a return-to-duty timeline.

• Authors: Kenneth J Ciuffreda, Diana P Ludlam, Preethi Thiagarajan, Naveen K Yadav, Jose Capo-Aponte
• Journal: Military medicine (Mil Med) Vol. 179 Issue 11 Pg. 1212-7 (Nov 2014) ISSN: 1930-613X [Electronic] England
• PMID: 25373043 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Review)
• Copyright: Reprint & Copyright © 2014 Association of Military Surgeons of the U.S.

Chemical References

• Biomarkers

Topics

• Biomarkers (analysis)
• Brain Concussion (diagnosis)
• Brain Injuries (diagnosis)
• Evoked Potentials, Visual (physiology)
• Humans
• Military Personnel
• Ocular Physiological Phenomena
• United States
• Vision Disorders (diagnosis)
• Vision, Ocular (physiology)