Abstract | OBJECTIVE: To review preventive measures and the current medical management of extrathyroidal manifestation of Graves disease and to provide an overview of potential immune therapies. METHODS: A literature review of investigative trials of treatments for Graves disease and its extrathyroidal manifestations. RESULTS: Given new knowledge of the stages of the autoimmune cascade responsible for the development of these extrathyroidal manifestations, the possibility has been raised of performing randomized trials of agents shown to provide benefits in other immune conditions. Two randomized trials on the efficacy of rituximab in moderate-to-severe Graves ophthalmopathy have reported conflicting results. CONCLUSION:
|
Authors | Vahab Fatourechi |
Journal | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
(Endocr Pract)
Vol. 20
Issue 12
Pg. 1333-44
(Dec 2014)
ISSN: 1530-891X [Print] United States |
PMID | 25370325
(Publication Type: Journal Article)
|