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Chromosomal translocations are mediated by canonical NHEJ in human cells.

Abstract
In contrast to mice, human cells require canonical NHEJ for DSB-induced chromosomal translocations.
Authors
JournalCancer discovery (Cancer Discov) Vol. 4 Issue 11 Pg. OF12 (Nov 2014) ISSN: 2159-8290 [Electronic] United States
PMID25367953 (Publication Type: News)
Copyright©2014 American Association for Cancer Research.
Topics
  • Cell Line
  • DNA Breaks, Double-Stranded
  • DNA End-Joining Repair
  • Humans
  • Translocation, Genetic

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