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LOX-1 unlocks human plasma cell potential.

Abstract
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is best known for promoting atherosclerosis. In this issue of Immunity, Joo et al. (2014) find that dendritic cells triggered through LOX-1 can directly support plasmablast production via the production of the cytokines APRIL and BAFF.
AuthorsRobert Brink
JournalImmunity (Immunity) Vol. 41 Issue 4 Pg. 507-8 (Oct 16 2014) ISSN: 1097-4180 [Electronic] United States
PMID25367564 (Publication Type: Journal Article, Comment)
Chemical References
  • H1N1 virus hemagglutinin
  • Hemagglutinin Glycoproteins, Influenza Virus
  • OLR1 protein, human
  • Scavenger Receptors, Class E
Topics
  • Animals
  • B-Lymphocytes (immunology)
  • Dendritic Cells (immunology)
  • Hemagglutinin Glycoproteins, Influenza Virus (immunology)
  • Humans
  • Immunoglobulin Class Switching (immunology)
  • Male
  • Scavenger Receptors, Class E (immunology)

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