[Efficacy of CO2 laser in the treatment of precancerous laryngeal lesions under phonomicrosurgery and its relative factors].

Abstract

OBJECTIVE:

To investigate the efficacy of CO2 laser treatment for patients with precancerous laryngeal lesions under phonomicrosurgery and to explore the points for attention in operation.

METHOD:

They were all treated with phonomicrosurgery techniques as mucosal epitheliumablation or mucosal stripping by using CO2 laser. Eight patients with laryngeal papilloma were excised by CO2 laser.

RESULT:

All patients were treated with CO2 laser surgery successfully. During follow-up of 6 to 39 months, all patients survived. Local recurrence or canceration were detected in 3 cases, of which 2 cases with laryngeal papilloma underwent CO2 laser treatment in one year post-operatively, while the other case with severe dysplasia underwent laryngeal vertical partial laryngectomy and post-operative radiotherapy one and half year postoperatively due to canceration. No local recurrence occurred until the last follow up. No severe complications such as dyspnea and hemorrhage occured.

CONCLUSION:

CO2 laser surgery is an effective and minimally invasive treatment for precancerous laryngeal lesions. Through selecting the appropriate patient and paying attention to the operation during surgery, the adhesion of vocal cord can be reduced or even be avoided after CO2 laser surgery.

• Authors: Qingjia Gu, Yong Feng, Xiaoxu Yu, Jian'gang Fan, Debing Li, Gang He
• Journal: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery (Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi) Vol. 28 Issue 15 Pg. 1142-4 (Aug 2014) ISSN: 2096-7993 [Print] China
• PMID: 25322603 (Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Carbon Dioxide

Topics

• Adult
• Aged
• Carbon Dioxide (therapeutic use)
• Female
• Follow-Up Studies
• Humans
• Laryngeal Neoplasms (surgery)
• Laryngectomy (methods)
• Laser Therapy
• Lasers, Gas (therapeutic use)
• Male
• Microsurgery
• Middle Aged
• Precancerous Conditions (surgery)
• Treatment Outcome