A rare presentation of hepatitis a infection with extrahepatic manifestations.

Abstract

Hepatitis A has a variety of associated extrahepatic manifestations that clinicians should be aware of for early diagnosis and treatment. We report a unique case of hepatitis A presenting with multiple extrahepatic manifestations not previously described in a single patient. A 34-year-old male presented with sudden onset of left sided facial pain, swelling, and skin rash, with diffuse body pains and muscle weakness, and was found to be positive for hepatitis A immunoglobulin M (IgM). He was initially started on antibiotics for concerns of bacterial parotitis but did not show any improvement. A punch biopsy of his mandibular rash and swelling was done which showed lymphohistiocytic infiltration with a few eosinophils. A trial of prednisone resulted in improvement of his symptoms. Clinicians should be aware to look for hepatitis A infection in a patient with atypical clinical picture causing a widespread systemic inflammatory response. Treatment with prednisone may result in resolution.

• Authors: Geetika Bhatt, Varrinder S Sandhu, Charlene K Mitchell
• Journal: Case reports in gastrointestinal medicine (Case Rep Gastrointest Med) Vol. 2014 Pg. 286914 ( 2014) ISSN: 2090-6528 [Print] United States
• PMID: 25295197 (Publication Type: Journal Article)