High-dose-rate brachytherapy for vaginal rhabdomyosarcoma using a personalized mold in a 20-month old patient.

Abstract

Treatment of vaginal rhabdomyosarcoma (RMS) with conservative approaches is presently the standard of care. Intravaginal high-dose rate brachytherapy is a very effective treatment while sparing the normal tissue to preserve growth, fertility and prevent organ dysfunction. In this report, we describe the management of an infant with Stage I vaginal RMS, treated with chemotherapy, maximal safe resection and intravaginal brachytherapy using a customized mold and MRI and CT-based three-dimensional (3D) conformal planning, followed by a critical review of the literature.

• Authors: Lara Hathout, Jamie Cohn, Laszlo Voros, Sae Hee Kim, Todd Heaton, Suzanne Wolden
• Journal: Pediatric blood & cancer (Pediatr Blood Cancer) Vol. 62 Issue 3 Pg. 531-2 (Mar 2015) ISSN: 1545-5017 [Electronic] United States
• PMID: 25284601 (Publication Type: Journal Article)
• Copyright: © 2014 Wiley Periodicals, Inc.

Topics

• Brachytherapy (instrumentation, methods)
• Female
• Humans
• Infant
• Precision Medicine (instrumentation, methods)
• Rhabdomyosarcoma (pathology, radiotherapy)
• Vaginal Neoplasms (pathology, radiotherapy)