Dopamine antagonists for nausea and vomiting: special considerations.

Abstract

The dopamine antagonists, particularly droperidol, are effective at treating N&V. Because dopamine plays many roles in the body, especially in the brain, a degree of alteration in mental status should be expected, especially with higher doses. Other less frequent side effects include QT prolongation. When given for non– chemotherapy-induced N&V treatment QT prolongation is rare. Higher doses warrant clinical awareness and ability to identify and treat prolonged QT and its sequelae. Invited authors for a following column will discuss QT prolongation and implications.

• Authors: Mark Welliver
• Journal: Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates (Gastroenterol Nurs) 2014 Sep-Oct Vol. 37 Issue 5 Pg. 361-4 ISSN: 1538-9766 [Electronic] United States
• PMID: 25271829 (Publication Type: Journal Article)

Chemical References

• Dopamine Antagonists
• Droperidol

Topics

• Dopamine Antagonists (therapeutic use)
• Droperidol (therapeutic use)
• Humans
• Nausea (drug therapy)
• Vomiting (drug therapy)