Nutrition in adult patients with inflammatory bowel disease.

Abstract

Seventy five percent of hospitalized patients with Crohn's disease suffer from malnutrition. One third of Crohn's disease patients have a body mass index below 20. Sixty percent of Crohn's disease patients have sarcopenia. However some inflammatory bowel disease (IBD) patients are obese or suffer from sarcopenic-obesity. IBD patients have many vitamin and nutrient deficiencies, which can lead to important consequences such as hyperhomocysteinemia, which is associated with a higher risk of thromboembolic disease. Nutritional deficiencies in IBD patients are the result of insufficient intake, malabsorption and protein-losing enteropathy as well as metabolic disturbances directly induced by the chronic disease and its treatments, in particular corticosteroids. Screening for nutritional deficiencies in chronic disease patients is warranted. Managing the deficiencies involves simple nutritional guidelines, vitamin supplements, and nutritional support in the worst cases.

• Authors: Xavier Hebuterne, Jerome Filippi, Stephane M Schneider
• Journal: Current drug targets (Curr Drug Targets) Vol. 15 Issue 11 Pg. 1030-8 ( 2014) ISSN: 1873-5592 [Electronic] United Arab Emirates
• PMID: 25266810 (Publication Type: Journal Article)

Chemical References

• Anti-Inflammatory Agents

Topics

• Adult
• Anti-Inflammatory Agents (adverse effects)
• Dietary Supplements
• Humans
• Inflammatory Bowel Diseases (complications, therapy)
• Malnutrition (etiology, therapy)