Abstract |
The use of biologic mesh in abdominal wall operations has gained popularity despite a paucity of outcome data. Numerous biologic products are available with virtually no clinical comparison studies. A retrospective study was conducted to compare patients who underwent abdominal wall hernia repair with Permacol™ (crosslinked porcine dermis) and Strattice™ (noncrosslinked porcine dermis). Of 270 reviewed patients, 195 were implanted with Permacol™ and 75 with Strattice™. Ventral hernia repairs comprised the majority (85% for Permacol, 97% for Strattice™). Postoperative infection rate was lower in the Strattice™ group (5 vs 21%, P < 0.01). In the Permacol™ group only, the overall complication rates were significantly higher in patients with infected versus clean wounds (55 vs 35%, P < 0.05) and in obese patients (body mass index 40 kg/m(2) or greater [57 vs 34%], P < 0.01). Short-term complication and recurrence rates were higher when mesh was used as a fascial bridge: 51 versus 28 per cent for Permacol™, 58 versus 20 per cent for Strattice™. The hernia recurrence was similar in both groups. In this review of patients undergoing abdominal hernia repair with biologic mesh, Strattice™ mesh was associated with a lower short-term complication rate compared with Permacol™, but the hernia recurrence rate was similar.
|
Authors | Amy W Cheng, Maher A Abbas, Talar Tejirian |
Journal | The American surgeon
(Am Surg)
Vol. 80
Issue 10
Pg. 999-1002
(Oct 2014)
ISSN: 1555-9823 [Electronic] United States |
PMID | 25264647
(Publication Type: Comparative Study, Evaluation Study, Journal Article)
|
Chemical References |
- Biocompatible Materials
- Permacol
- strattice
- Collagen
|
Topics |
- Adult
- Aged
- Aged, 80 and over
- Biocompatible Materials
- Collagen
- Female
- Hernia, Abdominal
(surgery)
- Hernia, Ventral
(surgery)
- Herniorrhaphy
(instrumentation, methods)
- Humans
- Male
- Middle Aged
- Postoperative Complications
(epidemiology, etiology, prevention & control)
- Recurrence
- Retrospective Studies
- Surgical Mesh
- Treatment Outcome
|