Abstract |
A fluorescent tridentate phosphine, BodP3 (2), forms rhenium complexes which effectively image cancer cells. Related technetium analogues are also readily prepared and have potential as dual SPECT/fluorescent biological probes.
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Authors | Laura H Davies, Benjamin B Kasten, Paul D Benny, Rory L Arrowsmith, Haobo Ge, Sofia I Pascu, Stan W Botchway, William Clegg, Ross W Harrington, Lee J Higham |
Journal | Chemical communications (Cambridge, England)
(Chem Commun (Camb))
Vol. 50
Issue 98
Pg. 15503-5
(Dec 21 2014)
ISSN: 1364-548X [Electronic] England |
PMID | 25248386
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Chemical References |
- Coordination Complexes
- Fluorescent Dyes
- Phosphines
- Rhenium
- Technetium
- phosphine
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Topics |
- Cell Line, Tumor
- Coordination Complexes
(analysis)
- Crystallography, X-Ray
- Fluorescent Dyes
(analysis)
- Humans
- Male
- Models, Molecular
- Multimodal Imaging
- Optical Imaging
- Phosphines
(analysis)
- Prostatic Neoplasms
(diagnosis)
- Rhenium
(analysis)
- Technetium
(analysis)
- Tomography, Emission-Computed, Single-Photon
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