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Re and (99m)Tc complexes of BodP3--multi-modality imaging probes.

Abstract
A fluorescent tridentate phosphine, BodP3 (2), forms rhenium complexes which effectively image cancer cells. Related technetium analogues are also readily prepared and have potential as dual SPECT/fluorescent biological probes.
AuthorsLaura H Davies, Benjamin B Kasten, Paul D Benny, Rory L Arrowsmith, Haobo Ge, Sofia I Pascu, Stan W Botchway, William Clegg, Ross W Harrington, Lee J Higham
JournalChemical communications (Cambridge, England) (Chem Commun (Camb)) Vol. 50 Issue 98 Pg. 15503-5 (Dec 21 2014) ISSN: 1364-548X [Electronic] England
PMID25248386 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
Chemical References
  • Coordination Complexes
  • Fluorescent Dyes
  • Phosphines
  • Rhenium
  • Technetium
  • phosphine
Topics
  • Cell Line, Tumor
  • Coordination Complexes (analysis)
  • Crystallography, X-Ray
  • Fluorescent Dyes (analysis)
  • Humans
  • Male
  • Models, Molecular
  • Multimodal Imaging
  • Optical Imaging
  • Phosphines (analysis)
  • Prostatic Neoplasms (diagnosis)
  • Rhenium (analysis)
  • Technetium (analysis)
  • Tomography, Emission-Computed, Single-Photon

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