HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Intralesional cryosurgery to treat keloid scars: results from a retrospective study.

AbstractBACKGROUND:
A variety of treatment modalities have been proposed to treat keloid scars, but outcomes are often disappointing. Intralesional cryosurgery may significantly reduce these scars.
OBJECTIVE:
To evaluate the clinical safety and efficacy of intralesional cryosurgery to treat keloid scars. Feedback from patients on pain, pruritus and aesthetic discomfort was recorded before and after treatment.
METHODS:
A total of 10 patients with 14 keloid scars resistant to conventional treatments were enrolled in a retrospective study between October 2007 and October 2013. The efficacy of this treatment was evaluated by measuring the reduction in scar surface.
RESULTS:
Scar surface was reduced by an average of 58.5% after intralesional cryosurgery treatment for all scars (average pre-operative keloid scar surface: 874.6 ± 954.1 mm2; average post-operative keloid scar surface: 505.8 ± 1,024.7 mm2; p = 0.002). Pain and aesthetic discomfort were significantly decreased after treatment in all patients (p = 0.008 and p = 0.012, respectively).
CONCLUSION:
Our data suggest that intralesional cryosurgery is an effective treatment for keloids.
AuthorsMarianne Chopinaud, Anne-Dominique Pham, Daniel Labbé, Laurence Verneuil, Charlotte Gourio, Hervé Bénateau, Anne Dompmartin
JournalDermatology (Basel, Switzerland) (Dermatology) Vol. 229 Issue 3 Pg. 263-70 ( 2014) ISSN: 1421-9832 [Electronic] Switzerland
PMID25248067 (Publication Type: Evaluation Study, Journal Article)
Topics
  • Adolescent
  • Adult
  • Aged
  • Cicatrix (complications, physiopathology)
  • Cryosurgery (methods)
  • Esthetics
  • Female
  • Follow-Up Studies
  • Humans
  • Keloid (etiology, pathology, surgery)
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Assessment
  • Severity of Illness Index
  • Treatment Outcome
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: