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Is there an association between a history of placental abruption and long-term maternal renal complications?

AbstractOBJECTIVE:
To investigate whether patients with a history of placental abruption have an increased risk for subsequent maternal long-term morbidity.
STUDY DESIGN:
A population-based study compared the incidence of long-term renal morbidity in cohort of women with and without a history of placental abruption. Deliveries occurred during a 25-year period, with a mean follow-up duration of 11.2 years. Renal morbidity included kidney transplantation, chronic renal failure, hypertensive renal disease, etc.
RESULTS:
During the study period 99 354 deliveries met the inclusion criteria; 1.8% (n = 1807) occurred in patients with a diagnosis of placental abruption. Patients with placental abruption did not have higher cumulative incidence of renal related hospitalizations, using Kaplan-Meier survival curve. During the follow-up period patients with a history of placental abruption did not have higher rate of renal morbidity (0.2% versus 0.1%; OR 1.8; 95% CI 0.6-4.8; p = 0.261). When performing a Cox proportional hazards model, adjusted for confounders such as parity and diabetes mellitus, a history of placental abruption was not associated with renal related hospitalizations (adjusted HR, 1.6; 95% CI, 0.6-4.2; p = 0.381).
CONCLUSION:
Placental abruption, even though considered a part of the "placental syndrome" with possible vascular etiology, is not a risk factor for long-term maternal renal complications.
AuthorsE S Arazi, R Kessous, I Shoham-Vardi, G Pariente, R Sergienko, E Sheiner
JournalThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (J Matern Fetal Neonatal Med) Vol. 28 Issue 14 Pg. 1641-6 ( 2015) ISSN: 1476-4954 [Electronic] England
PMID25234099 (Publication Type: Journal Article)
Topics
  • Abruptio Placentae
  • Adult
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Israel
  • Kaplan-Meier Estimate
  • Pregnancy
  • Proportional Hazards Models
  • Renal Insufficiency, Chronic (epidemiology, etiology)
  • Retrospective Studies
  • Risk Factors

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