The rate of open converted
cholecystectomy was 15.7 %. In multivariate analysis,
cholecystitis (OR 1.908, 95 % CI 1.390-6.388, p = 0.005), mechanical
lithotripsy (OR 6.129, 95 % CI 1.867-20.123, p < 0.005), and two or more choledocholithiases (OR 2.202, 95 % CI 1.097-4.420, p = 0.026) revealed significant risk factors for conversion to open
cholecystectomy. Analyzing the risk factors for open converted
cholecystectomy according to duration from endoscopic stone removal to
cholecystectomy (within 2 weeks, between 2 and 6 weeks, and beyond 6 weeks), acute
cholangitis (OR 3.374, 95 % CI 1.267-8.988, p = 0.015),
cholecystitis (OR 3.127, 95 % CI 1.100-8.894, p = 0.033), and mechanical
lithotripsy (OR 17.504, 95 % CI 3.548-86.355, p < 0.005) were related to open converted
cholecystectomy in ≤2 weeks group.
CONCLUSIONS: For patients who need
cholecystectomy after endoscopic removal of
choledocholithiasis, endoscopic retrograde cholangiography-related factors predictive for open converted
cholecystectomy are helpful in planning the appropriate timing of surgery.