Abstract | PURPOSE: METHOD: The study was a randomised, controlled, study design. Patients ≥16 years scheduled for allogeneic stem cell transplantation were included consecutively and randomised to experimental group receiving OC combined with Caphosol(®) (n = 20) or control group receiving OC only (n = 20). OC was given from start to end of HDCT. Caphosol(®), from day 0 to day 21. RESULT: There were no significant differences regarding age or gender between the groups. Mucositis was assessed with the World Health Organisation (WHO) grading scale. Pain was assessed with a 10 cm visual analogue scale (VAS) from 0 = no pain to 10 = worst imaginable pain. Start and duration of therapy with pain relieving drugs, serum C-reactive protein values, and number of days of hospitalisation were collected from the medical records. Data on OM, oral pain, use of i.v. opioids and total parenteral nutrition were collected during 22 days. There was no significant difference between the groups on OM, oral pain, use of i.v. opioids or TPN between the groups. CONCLUSION: The study showed no additional effect of combining Caphosol(®) with OC.
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Authors | Anncarin Svanberg, Kerstin Öhrn, Gunnar Birgegård |
Journal | European journal of oncology nursing : the official journal of European Oncology Nursing Society
(Eur J Oncol Nurs)
Vol. 19
Issue 1
Pg. 50-3
(Feb 2015)
ISSN: 1532-2122 [Electronic] Scotland |
PMID | 25224595
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2014 Elsevier Ltd. All rights reserved. |
Chemical References |
- Calcium Phosphates
- Mouthwashes
|
Topics |
- Adult
- Calcium Phosphates
(therapeutic use)
- Cryotherapy
- Female
- Hematopoietic Stem Cell Transplantation
(adverse effects)
- Humans
- Leukemia
(pathology, therapy)
- Male
- Middle Aged
- Mouthwashes
(therapeutic use)
- Pilot Projects
- Stomatitis
(etiology, prevention & control)
- Transplantation Conditioning
(adverse effects)
- Treatment Outcome
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