Abstract | OBJECTIVES: MATERIALS AND METHODS: RESULTS: The acute systolic blood pressure was significantly increased, 148 (141-168) vs 140 (130-147) mmHg post- stroke. Angiotensin I, renin and aldosterone levels were significantly lower, angiotensin II was unchanged, and ACE activity was higher in the acute phase compared to post- stroke. No differences in RAAS were detected between jugular and cubital plasma levels. Jugular venous plasma levels of epinephrine and cortisol were elevated in the acute phase compared to cubital levels (P < 0.05). CONCLUSION: Increased epinephrine and cortisol levels in the jugular vein blood may reflect a higher peripheral turnover. The observed changes in RAAS in the acute stroke phase are consistent with responses to increased blood pressure.
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Authors | C Back, K L Thiesen, K Skovgaard, L Edvinsson, L T Jensen, V A Larsen, H K Iversen |
Journal | Acta neurologica Scandinavica
(Acta Neurol Scand)
Vol. 131
Issue 2
Pg. 132-9
(Feb 2015)
ISSN: 1600-0404 [Electronic] Denmark |
PMID | 25214428
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. |
Chemical References |
- Biomarkers
- Angiotensin II
- Aldosterone
- Renin
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Topics |
- Aged
- Aged, 80 and over
- Aldosterone
(blood)
- Angiotensin II
(blood)
- Animals
- Biomarkers
(blood)
- Blood Pressure
- Female
- Humans
- Hypertension
- Male
- Middle Aged
- Renin
(blood)
- Renin-Angiotensin System
(physiology)
- Stroke
(blood, physiopathology)
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