Abstract | BACKGROUND: METHODS: RESULTS: The overall incidence of headache during the 7-day period was 5 patients (3.7%) in the control group and 11 patients (8.2%) in the study group, which is not statistically significant (X(2) = 2.393 and p = 0.122. The severity of headache also shows no statistical significance (2.2% in cases versus 6% in controls; z = 1.53, p = 0.126). The intensity of headache reported at the 24 hours (z = 0.698; p = 0.485), 72 hours (z = 0.849; p = 0.396), and 7 days (z = 0.008; p = 0.994) was not different. There also was no difference in the incidence of backache in the two groups. CONCLUSION: In contrast to other studies that showed the efficacy of intravenous dexamethasone in the prevention and treatment of PDPH, our study did not show any significant effect of prophylactic epidural injection of dexamethasone in prevention of PDPH. However regarding the low number of PDPH in routine cases, evaluation of this intervention in groups with a high incidence of PDPH by using of particulate steroids is recommended to confirm these preliminary findings.
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Authors | Atabak Najafi, Sara Emami, Mohammadreza Khajavi, Farhad Etezadi, Farsad Imani, Mahbod Lajevardi, Pejman Pourfakhr, Reza Shariat Moharari |
Journal | Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists
(Acta Anaesthesiol Taiwan)
Vol. 52
Issue 3
Pg. 95-100
(Sep 2014)
ISSN: 1875-452X [Electronic] China (Republic : 1949- ) |
PMID | 25199696
(Publication Type: Journal Article, Randomized Controlled Trial)
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Copyright | Copyright © 2014. Published by Elsevier B.V. |
Chemical References |
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Topics |
- Adult
- Anesthesia, Spinal
(adverse effects)
- Dexamethasone
(administration & dosage)
- Epidural Space
- Female
- Humans
- Male
- Post-Dural Puncture Headache
(prevention & control)
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