A complicated case of vascular Pythium insidiosum infection treated with limb-sparing surgery.

Abstract

INTRODUCTION:

Pythiosis is a serious life- and limb-threatening infection endemic to Thailand, but rarely seen in the Western hemisphere. Here, we present a unique case of vascular pythiosis initially managed with limb-sparing vascular bypass grafts complicated by a pseudoaneurysm in our repair.

PRESENTATION OF CASE:

The patient is a 17 year-old Jamaican male with severe aplastic anemia. He sustained a minor injury to his left leg while fishing in Jamaica, which evolved to become an exquisitely tender inguinal swelling. His physical exam and imaging were significant for arteriovenous fistula with limb ischemia. Pathology obtained during surgery for an extra-anatomic vascular bypass showed extensive invasion by Pythium insidiosum. He later developed a pseudoaneurysm at the site of proximal anastomosis and required urgent intervention.

DISCUSSION:

This patient presented with a rare, but classic case of vascular pythiosis, which was unrecognized at the time of presentation. A variety of therapeutic modalities have been used to treat this disease, including antibiotics, antifungals, and immunotherapy, but the ultimate management of vascular pythiosis is surgical source control.

CONCLUSION:

A high index of suspicion in susceptible patients is needed for timely diagnosis of vascular pythiosis to achieve optimal source control.

• Authors: Jenny H Pan, Sid P Kerkar, Michael P Siegenthaler, Marybeth Hughes, Prakash K Pandalai
• Journal: International journal of surgery case reports (Int J Surg Case Rep) Vol. 5 Issue 10 Pg. 677-80 ( 2014) ISSN: 2210-2612 [Print] Netherlands
• PMID: 25194603 (Publication Type: Journal Article)
• Copyright: Published by Elsevier Ltd.