Abstract | PURPOSE: To evaluate the predictive power of luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, testicular biopsy histology and male age were evaluated with respect to the success of sperm retrieval in a microdissection testicular sperm extraction (microTESE) procedure, pregnancy and live birth rates. MATERIALS AND METHODS: We examined the data of 131 infertile men with non-obstructive azoospermia, who have undergone microTESE operation. The men were classified into two groups based on serum follicle-stimulating hormone (FSH) levels ≤ 15 mIU/mL (group 1) and > 15 mIU/mL (group 2). RESULTS: Group 1 consisted of 59 patients (mean age 36.2 ± 6.2 years) and group 2 consisted of 72 (mean age 38.8 ± 7.4 years) patients. Sperm retrieval and pregnancy rates were 66.1% and 16.9% in normal FSH group, respectively. These parameters were higher than those of men with FSH > 15 (43% and 8.3%, respectively). Only 128 patients had histopathological diagnosis. Sperm was retrieved from 12/30 (40%) patients with maturation arrest, 9/29 (31.03%) patients with seminiferous tubules atrophy, 14/40 (35%) patients with sertoli cell only syndrome and 13/13 (100%) of patients with hypospermatogenesis. There was no statistically significant difference in pathological diagnosis between pregnancy and live birth rates. CONCLUSION: These results demonstrate that there is a significant difference with sperm retrieval, pregnancy rates and live birth rates comparing the FSH levels. Histopathological findings did not associate with successful microTESE, pregnancy rates and live birth rates.
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Authors | Mehmet Erol Yildirim, Akif Koc, Ikbal Cekmen Kaygusuz, Hüseyin Badem, Omer Faruk Karatas, Ersin Cimentepe, Dogan Unal |
Journal | Urology journal
(Urol J)
Vol. 11
Issue 4
Pg. 1825-8
(Sep 06 2014)
ISSN: 1735-546X [Electronic] Iran |
PMID | 25194084
(Publication Type: Journal Article)
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Chemical References |
- Follicle Stimulating Hormone
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Topics |
- Adult
- Age Factors
- Azoospermia
(blood, pathology, therapy)
- Biopsy
- Female
- Follicle Stimulating Hormone
(blood)
- Humans
- Live Birth
- Male
- Microdissection
- Middle Aged
- Oligospermia
(pathology)
- Pregnancy
- Pregnancy Rate
- Sertoli Cell-Only Syndrome
(pathology)
- Sperm Retrieval
- Testis
(pathology)
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