Daptomycin in the treatment of prosthetic joint infection by Enterococcus faecalis: safety and efficacy of high-dose and prolonged therapy.

Abstract

Enterococci are implicated in less than 2.3% of prosthetic joint infections. These infections can be difficult to treat and therapeutic failures are not uncommon. In these situations, daptomycin is a safe and effective alternative. We present a clinical case with a successful response to the prolonged use of high-dose daptomycin.

• Authors: José Ramón Yuste, Milena Quesada, Pablo Díaz-Rada, José Luis Del Pozo
• Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases (Int J Infect Dis) Vol. 27 Pg. 65-6 (Oct 2014) ISSN: 1878-3511 [Electronic] Canada
• PMID: 25192907 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Chemical References

• Anti-Bacterial Agents
• Daptomycin

Topics

• Adult
• Anti-Bacterial Agents (administration & dosage)
• Daptomycin (administration & dosage)
• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Enterococcus faecalis (isolation & purification)
• Gram-Positive Bacterial Infections (drug therapy, microbiology)
• Humans
• Male
• Prosthesis-Related Infections (drug therapy, microbiology)