Abstract | OBJECTIVE: To assess the clinical and urodynamic outcomes of patients with low-compliance neurogenic bladder who were treated with sigmoid bladder augmentation (SBA) over a long-term follow-up. MATERIALS AND METHODS: We retrospectively reviewed 52 patients with low-compliance neurogenic bladder who underwent SBA alone or with antireflux techniques in our hospital from 2006 to 2014. Clinical outcomes regarding bladder function, incontinence, medications, catheterization schedules, subsequent interventions, bowel function, and patient satisfaction were addressed. RESULTS: The mean follow-up was 49 months. All patients experienced significant increases in safe cystometric capacity from 113.8 ± 65.9 mL to 373.1 ± 66.7 mL (P <.001), bladder compliance from 2.96 ± 1.55 mL/cm H2O to 14.07 ± 5.45 mL/cm H2O (P <.001), and decreases in creatinine from 88.1 ± 38.6 μmol/L to 77.1 ± 30.4 μmol/L (P <.001) compared with those before surgery. Six patients (11.5%) required anticholinergic medicine to control neurogenic detrusor overactivity, and 11 (21.1%) had recurrent febrile urinary tract infections after SBA. Among 47 prehydronephrosis patients (grade I-II in 10 and III-V in 37), 16 still had minor hydronephrosis after SBA, but the hydronephrosis had been improved significantly (all posthydronephroses were grade I-II instead). All patients reported significant improvements in constipation, and no patient had obvious metabolic acidosis or bladder perforation after SBA. All patients expressed extreme satisfaction with the operation. CONCLUSION:
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Authors | Peng Zhang, Yong Yang, Zhi-jin Wu, Ning Zhang, Chao-hua Zhang, Xiao-dong Zhang |
Journal | Urology
(Urology)
Vol. 84
Issue 3
Pg. 697-701
(Sep 2014)
ISSN: 1527-9995 [Electronic] United States |
PMID | 25168554
(Publication Type: Journal Article)
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Copyright | Copyright © 2014 Elsevier Inc. All rights reserved. |
Chemical References |
- Cholinergic Antagonists
- Creatinine
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Topics |
- Adolescent
- Adult
- Child
- Cholinergic Antagonists
(therapeutic use)
- Colon, Sigmoid
(transplantation)
- Creatinine
(urine)
- Female
- Follow-Up Studies
- Humans
- Hydronephrosis
(surgery)
- Male
- Middle Aged
- Patient Satisfaction
- Recurrence
- Retrospective Studies
- Treatment Outcome
- Urinary Bladder
(pathology)
- Urinary Bladder, Neurogenic
(surgery)
- Urinary Tract Infections
(pathology)
- Urologic Surgical Procedures
- Young Adult
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