Abstract | BACKGROUND: MATERIALS AND METHODS: The chemical victims were divided into the 2 groups of 30:A group with mild to moderate pulmonary symptoms and other group with moderate to severe symptoms and compared with 3(rd) group as healthy controls. After preparing our samples and using the SP kit, final analysis was performed with enzyme-linked immunosorbent assay reader. RESULTS: The Concentration of circulatory SP levels in the chemical patients was 2.86 ± 1.47 ng/ml and had not a significant difference with the control group (3.15 ± 1.03 ng/ml) (P > 0.05). The circulatory SP levels were 2.48 ± 0.92 ng/ml and 3.28 ± 1.73 ng/ml in patients with moderate to severe symptoms and mild to moderates (P < 0.05) respectively. CONCLUSION: The SP may have a role in pulmonary complications of mustard gas. The lower level of SP in the moderate to severe patients may be due to corticosteroid consumption in such severe cases. However, further studies are needed to clarify the roles and mechanism of SP in this setting.
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Authors | Bita Najafian, Majid Shohrati, Ali Amini Harandi, Shiva Mahyar, Isa Khaheshi, Mostafa Ghanei |
Journal | Advanced biomedical research
(Adv Biomed Res)
Vol. 3
Pg. 137
( 2014)
ISSN: 2277-9175 [Print] India |
PMID | 25161984
(Publication Type: Journal Article)
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